Analytical development equipment

The API chemical development is backed-up by comprehensive analytical development capabilities utilizing state-of-the-art R&D labs. Analytical development team employ the latest and the most advanced and modern techniques, these include:

• Wet Chemistry Analyses (colorimetry, gravimetric, titrimetric)
• Elemental Analysis
• HPLC (systems equipped with UV-VIS, PDA, RI, CD and FL detectors)
• UPLC (systems equipped with PDA / ELSD detectors)
• GC-FID, HSGC-FID
• Ionic Chromatography
• Prep-HPLC
• Mass Spectrometry (HPLC-MS, UPLC-QTOF and GC-MS)
• NMR (up to 500 MHz)
• FT-IR Spectroscopy
• UV-VIS Spectroscopy
• Polarimetry
• Thermal Analysis (TGA, DSC)
• Particle Size Analysis (Malvern® mastersizer, Laser Diffraction and Sieve-Pipette method)
• Optical Microscopy
• X-Ray Crystallography
• Climatic Chambers (for ICH stability studies)

Angelini adheres to Quality by Design (QbD) principles to support the whole API lifecycle in development, validation and transfer of analytical methods.